CoQ10 May Reduce Afib in Heart Failure Patients


A new randomized trial of heart failure patients found a benefit in the reduction of atrial fibrillation when CoEnzyme Q10 is supplemented.  Atrial fibrillation is a common cardiac arrhythmia which could occur in almost 27% of patients with heart failure.

128 women and men with heart failure who were being treated with ACE inhibitors, beta-blockers, statins and/or additional drugs participated in this trial.  At the time of entry into the study and at 6 and 12 months ambulatory electrocardiogram monitoring was done for a 24 hour period.  In addition inflammatory markers were assessed with blood measurement.  62 participants received a 30 mg dose of CoQ10 for 1 year.

At the end of the trial year, 3 participants who had been supplementing with CoQ10 and 12 participants who had not been receiving the CoQ10 had experienced episodes of atrial fibrillation.  MDA levels, a marker of oxidative stress, were reduced in the CoQ10 group but had remained unchanged in the group who had not been supplementing.

Further studies are needed.

ATP or adenosine triphosphate is the main molecule that serves as an energy source for all biochemical and physiological processes in the body. ATP is manufactured via a complex process in a tiny part of the cell known as the mitochondria. Within the mitochondria, CoQ10 plays a major role as part of the electron transport chain, the major metabolic pathway for making energy in every cell. The process of electron transport produces free radicals that may cause damage to healthy cells. CoQ10, as an antioxidant helps neutralize these free radicals helping to support continued function of the mitochondria and other important cellular components. CoQ10 has been extensively studied for its ability to support cardiovascular function.  It has been shown to help support the heart muscle, normal, healthy blood pressure a well as provide benefit to individual’s taking cholesterol lowering medications. These medications have been shown to reduce blood levels of CoQ10.



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