Inflammation typically seen in Type 1 Diabetes may be reduced by Omega-3 Essential Fatty Acids according to new research. In a study involving mice supplementation with Omega 3 led to long-term improvements in insulin and glucose levels.
Female non-obese diabetic mice were fed a control diet which was supplemented with either 10% arachidonic acid (an Omega 6 Essential Fatty Acid) or 10% EPA/DHA (an Omega 3 Essential Fatty Acid). This regimen lasted for 35 weeks and started when the mice were 5 weeks old. To test insulin tolerance Glucose tolerance tests were used. 80% of the female non-obese diabetic mice (NOD) who were fed a regular diet had developed diabetes by the age of 40 weeks however only 33% of the mice who received the EPA/DHA diet were considered diabetic.
Researchers looked at how the EPA/DHA would affect the human CD4+T cells, these cells play an essential role in the adaptive immune system. Researchers found that Omega 3 Essential Fatty Acids had the same effect on differentiating CD4+T cells isolated from Type 1 Diabetics as those seen in the NOD mice suggesting the Omega 3 Essential Fatty Acids may potentially be used as a therapy in addressing Type 1 Diabetes.
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