Antioxidants Might Help in Early Diabetic Kidney Disease

Antioxidants and Kidney DiseaseA recent meta-analysis and review found supplementation with antioxidants, like Vitamin E, may reduce the loss of a specific protein, albumin, in a patient’s urine.  The excretion of albumin is an early sign of diabetic kidney disease (DKD).

The purpose of the meta-analysis and review was to determine if antioxidant supplementation would slow the progression of DKD to end state kidney disease (ESKD).  DKD is the prime cause of ESKD.  Approximately half of all long-term diabetics end up developing some form of kidney damage over their lifetime.  Most trials reviewed used Vitamin E and or Vitamin E as well as B6, Zinc, Alpha Lipoic Acid, Silymarin and reduced Glutathione.  Antioxidants were used either individually or in combination.

Most antioxidants showed some benefit in reducing Urinary Albumin Excretion (UAE).  Vitamin E showed the most consistent benefit.  Researchers found it difficult to reach any strong conclusions due to the diversity in study designs, trial sizes, outcome measures to name a few of the meta-analysis challenges.  However researchers did find a benefit of antioxidant therapy (especially Vitamin E) on early signs of renal damage.

Further studies are needed.




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I have been involved in the Wellness Industry for over 25 years. I am a Certified Dietary Supplement Specialist and regularly lectures at various higher learning institutions on basic vitamin/mineral/herbal supplement facts. I became involved in the industry after being diagnosed with chronic fatigue syndrome. Not satisfied with conventional treatment methods, I began to learn about natural remedies and slowly began to see changes in my condition. Driven by my own results with natural products I developed a passion to pass on those same benefits to others who also suffered any number of ailments and wanted a natural treatment alternative that offered results. In store, myself and my highly trained staff of vitamin specialists offer free consultations and vitamin fitting options that create lifestyle programs that customers can live and thrive with for noticeable benefits. By doing extensive research about quality the store is able to cut the guess work out for out customers. Instead of offering a multitude of different brand alternatives, we only offer the highest quality products that way insuring optimal results for the customer. The store’s fundamental philosophy focuses on integrity selling and results. Please feel free to call on us to answer all of your vitamin and nutritional needs.

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