Long Term Melatonin Supplementation Could Benefit Those With High Cholesterol

Melatonin and High CholesterolA new systematic review was undertaken to determine how supplementation with Melatonin affected blood lipids.  Researchers reviewed eight Random Controlled Trials.  Participants in these studies ranged in age from 16 years old to 74 years old and with the exception of one of the studies included both men and women (one of the studies included only male participants).

A significant relationship between supplementation with Melatonin and reductions in total cholesterol levels as well as a reduction in triglycerides was seen in this meta-analysis.  The mechanism for lipid reduction associated with Melatonin was attributed to Melatonin’s ability to suppress visceral fat which ultimately prevented cholesterol synthesis and absorption while improving LDL receptor activity and inhibiting metabotropic receptors which aid in the transport of fatty acids.  A noticeable reduction was also seen in VLDL (very low-density lipoprotein) cholesterol in the participants who supplemented with Melatonin.  Researchers believe this effect occurs when intestinal cholesterol absorption has been suppressed.  Reductions in triglycerides were also seen in participants who supplemented with 8mg doses of Melatonin for a period of 8 weeks.

Researchers concluded that Melatonin supplementation had a significant effect on lowering total cholesterol and triglycerides and a minor effect on improving HDL cholesterol and LDL cholesterol as well as providing protection from LDL oxidation which may contribute to Melatonin’s supporting role in preventing atherosclerosis.  LDL oxidation is a major activation step in atherosclerosis development.  Additionally, researchers found considerable evidence that point to Melatonin’s ability to act as a strong antioxidant.

Further studies are needed to determine all the benefits Melatonin may provide for supporting a healthier lipid profile.





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I have been involved in the Wellness Industry for over 25 years. I am a Certified Dietary Supplement Specialist and regularly lectures at various higher learning institutions on basic vitamin/mineral/herbal supplement facts. I became involved in the industry after being diagnosed with chronic fatigue syndrome. Not satisfied with conventional treatment methods, I began to learn about natural remedies and slowly began to see changes in my condition. Driven by my own results with natural products I developed a passion to pass on those same benefits to others who also suffered any number of ailments and wanted a natural treatment alternative that offered results. In store, myself and my highly trained staff of vitamin specialists offer free consultations and vitamin fitting options that create lifestyle programs that customers can live and thrive with for noticeable benefits. By doing extensive research about quality the store is able to cut the guess work out for out customers. Instead of offering a multitude of different brand alternatives, we only offer the highest quality products that way insuring optimal results for the customer. The store’s fundamental philosophy focuses on integrity selling and results. Please feel free to call on us to answer all of your vitamin and nutritional needs.

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