Melatonin Supplementation Benefits Alzheimer’s Disease Patients

Alzheimers and MelatoninA benefit in cognitive function and sleep for both men and women with mild to moderate Alzheimer’s Disease, was seen in a double blind placebo controlled study using a sustained-  release melatonin.

Melatonin is a hormone released from a gland found in the brain called the pineal gland.  Melatonin regulates the body’s circadian rhythm and helps initiate sleep.  Sleep plays an essential role in memory consolidation.

73 patients who were receiving drug therapy for Alzheimer’s disease participated in this study.  The participants received a prolonged release melatonin or a placebo every night for 24 weeks.

Pittsburgh Sleep Quality Index assessments, Mini-Mental State Examination, Instrumental Activities of Daily Living and Alzheimer’s Disease Assessment Scale Cognition tests were given before the study, 12 weeks into the study and at the end of the study.  In addition a sleep diary which kept tract of awakenings midsleep was completed.

After the 24 weeks, participants who had received the melatonin showed significant cognitive performance in comparison to participants who received the placebo.  Also the melatonin group had improved sleep efficiency compared to prior to the study’s onset.  For 13 individuals who had insomnia at the start of the trial the melatonin improved all their test results significantly.

Researchers believe that improved sleep efficiency may lead to less risk of beta amyloid deposits increases in the ability of the body to clear beta amyloid from the brain.  Ultimately this slows Alzheimer’s disease progression.



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I have been involved in the Wellness Industry for over 25 years. I am a Certified Dietary Supplement Specialist and regularly lectures at various higher learning institutions on basic vitamin/mineral/herbal supplement facts. I became involved in the industry after being diagnosed with chronic fatigue syndrome. Not satisfied with conventional treatment methods, I began to learn about natural remedies and slowly began to see changes in my condition. Driven by my own results with natural products I developed a passion to pass on those same benefits to others who also suffered any number of ailments and wanted a natural treatment alternative that offered results. In store, myself and my highly trained staff of vitamin specialists offer free consultations and vitamin fitting options that create lifestyle programs that customers can live and thrive with for noticeable benefits. By doing extensive research about quality the store is able to cut the guess work out for out customers. Instead of offering a multitude of different brand alternatives, we only offer the highest quality products that way insuring optimal results for the customer. The store’s fundamental philosophy focuses on integrity selling and results. Please feel free to call on us to answer all of your vitamin and nutritional needs.

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