Low Omega-3 Levels Linked to Prenatal Depression

Omega-3 and Prenatal DepressionA new study shows an Omega-3 deficiency as well as increased inflammation may be associated with prenatal depression (PND).  Also an Omega-3 deficiency may result in longer episodes of depression.

33 women (17 women with PND and 16 healthy women) in their second and third trimesters of pregnancy participated in this study.  Their inflammatory markers, tumor necrosis factor alpha (TNF-a) as well as their Omega-3 levels were measured.  The women who experienced PND had significantly higher TNF-a levels and significantly lower Omega-3 levels.

These finds confirm other observational studies that show higher levels of total Omega-3 (DHA  and EPA) seem to act as “protective factors” against major depressive disorder (MDD).  Also larger DHA levels found in breast milk and increasing the consumption of DHA rich foods, like seafood, have been shown as links to decreased risks of postpartum depression.  Omega-3 deficiencies seen during pregnancy may also increase the length of the depressive episodes which could last even into the first year after delivery.  This could lead to psychosocial dysfunction, suicide, poor mother-child relationships, and destructive behaviors like alcohol and drug abuse according to this study.

Future larger sample size studies are needed to replicate the findings in this study.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

 

 

 

Meta-Analysis Supports Potential of Omega-3s for ADHD

Omega-3 and ADHDAccording to a new meta-analysis of “gold standard” clinical studies, Omega-3 essential fatty acid supplements could improve symptoms and cognitive performance in adolescents and children with attention deficit hyperactivity disorder (ADHD).

Data taken from seven randomized controlled trials (RCTs) and involving over 500 youth was analyzed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.  The data used was taken from established scientific literature databases to insure only appropriate studies were included in this meta-analysis.

Researchers found that supplementation with Omega-3 essential fatty acids significantly improved hyperactivity and inattention symptoms. Improvements in hyperactivity were only seen when doses of EPA (eicosapentaenoic acid) were over 500 mg/day.  Additionally data from case-control studies were also taken to determine if Omega-3 levels were associated with ADHD.  Results showed that adolescents and children with ADHD had lower levels of EPA, DHA and total Omega-3.  Improvements in certain measures of cognitive performance were also associated with Omega-3 supplementation.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

Omega-3 and Arthritis: Study Finds Link Between Fish Consumption and Joint Disorder

Arthritis Omega-3New data finds regular consumption of fish rich in Omega-3 Essential Fatty Acids may reduce symptoms of Rheumatoid Arthritis.

Over 170 patients were assessed for Rheumatoid Arthritis scores using the DAS28-CRP scale.  Their intake of Omega-3 Essential Fatty Acids were assessed using a food frequency questionnaire

Researchers found a dose-response relationship between RA scores and Omega-3 Essential Fatty Acid intake, increasing Omega-3 Essential Fatty Acids reduced the activity of the disease.

More studies are needed.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

Omega-3 Deficient Teenagers May Become Anxious Adults

Omega 3 AnxietyA new study using mice has found low Omega-3 in adolescent mice may lead to behavioral problems in adulthood.

Using a mouse model which mimicked a dietary deficiency of Omega-3 Essential Fatty Acids during childhood and adolescence, researchers found significant increases in anxiety and anhedonia (the inability to experience pleasure from activities usually found enjoyable).  The increases in these conditions can lead to decreases in specific cognitive functions during adulthood.  Researchers found switching the diet of the mice to one lacking Omega-3’s during adolescence led to lower Poly Unsaturated Fatty Acid (PUFA) levels in various areas of the brain during the adulthood of the mice.  These lower Omega-3 levels in these affected areas of the brain impacts a signaling mechanism known as mGlu5-endocannabinoid.  This signaling mechanism results in the changes seen in cognitive and emotional functions.

Omega-3 Essential Fatty Acid deficiency is widely believed to be a major risk factor associated with conditions like schizophrenia, bipolar disorder and depression.  Current research has shown the importance of high Omega-3 status during important development periods like perinatal and adolescent life stages.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

Omega-3 May Shorten Hospital Stay in Heart Surgery Patients

Strong Hearth ChalkboardA new review has found that a reduction in the time spent in the hospital and a reduction in the risk of complications was seen in open heart surgery patients supplementing Omega-3 Essential Fatty Acids daily.

19 randomized, controlled trials were reviewed.  Reductions of 1.4 days in the length of time spent in the hospital as well as a 22% reduction in the incidence of Post-Operative Atrial Fibrillation (POAF) were seen.  Dosages of 2 grams/day were best for reducing arrhythmias.  Researchers did acknowledge that the shorter recovery time could be due to the reduction in POAF.  However the researchers strongly felt the findings of this meta-analysis show promise for using Omega-3 Essential Fatty Acids as a perioperative therapy (therapy given before, during and after a surgical procedure).

Researchers concluded that it would make sense for patients exposed to extra-corporeal circulation (circulation of the blood outside the body, as through a heart lung machine) to experience stronger systemic inflammatory response syndrome since they come into contact with blood with non-endothelial surfaces.  The Omega-3 Essential Fatty Acids showed a positive impact on systemic inflammation reduction, the reductions seen in POAF, the shorter lengths of hospitals stays as well as other unknown improvements in clinical outcomes.

Larger scale, well designed, randomized, controlled trials are needed.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

 

Omega-3 Could Aid Alzheimer’s Prevention

Omega-3 and Alzheimer's DiseaseNew research finds individuals with high Omega-3 intakes have an increase in blood flow in the brain suggesting a link might exist between Omega-3 and Alzheimer’s Disease.

Over 160 randomly selected people participated in this trial.  These participants were taken from clinics and their brain function was studied using single photon emission computed tomography (SPECT).  SPECT measures blood perfusion in the brain.  128 regions of the brain were used to collect data on the correlation between Omega-3 blood levels as well as blood flow in the brain.  Resting-state scans were performed while participants were sitting in a dimly lit room with ambient noise and with their eyes open.  For on-task scans participants completed Continuous Performance Tests (CPTs) while the scans were performed.

Significant statistical relationships were found between EPA and DHA (Omega-3 Essential Fatty Acids)  levels in the blood and cerebral perfusion in various regions of the brain: areas known for memory encoding and retrieval (parahippocampal gyrus), areas for episodic memory, visuospatial processing, and aspects of consciousness (the right preuneus), and areas associated with bodily locomotion and posture (vermis subregion).

Researchers concluded that Omega-3 Essential Fatty Acids (EPA and DHA) may improve brain physiology which in turn leads to better cognitive reserves.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

Omega-3 and Perinatal Depression

Omega-3 Peri Natal DepressionA new meta-analysis has found a critical role for Omega-3 in decreasing pre and post-natal depression (perinatal).  This meta-analysis also found cases of depression might be associated with a higher Omega-6/Omega-3 ratio.  This translates into a potential new way to treat perinatal depression (PND) because of Omega-3’s neuroplastic, anti-inflammatory and safety effects.

12 eligible studies which became available in December of 2016 were analyzed.  Researchers found a significant reduction in the total of Omega-3 Essential Fatty Acids and a significant increase in the Omega-6 to Omega-3 ratios in the women who were experiencing PND.  Researchers concluded that the results of this meta-analysis emphasize how important Essential Fatty Acids are in clinical depression.  They pointed out that the brain is enriched with Omega-3 Essential Fatty Acids which regulate many biological processes like neuroinflammation, Neuroplasticity and neurotransmission and hence also regulate mood as well as cognitive function.  They further pointed out that both EPA and DHA and their benefits for reducing depression have been studied and recognized for many years, the imbalance between Omega-3 and Omega-6 as seen in this meta-analysis need to be examined more fully as a possible prediction of metal health in women during and after pregnancy.  Modern diets often show a profound imbalance between Omega-6 and Omega-3 Essential Fatty Acids, as much as 10-20:1.  Anthropological studies indicate humans evolved with a dietary ratio of Omega-6’s/Omega-3’s of 1:1.

Clinical trials are needed to test the therapeutic effects of Omega-3’s in the treatment of PND.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com