Omega-3 May Help Fight Fatty Liver Disease

Fatty Liver DiseaseAccording to a new pilot study a high dose Omega-3 supplement may improve Non-Alcoholic Fatty Liver Disease (NAFLD) markers.

This pre-specified sub study of the WELCOME Trial (Wessex Evaluation of Fatty Liver and Cardiovascular markers in NAFLD with Omacor Therapy), a double blinded randomized controlled trial, looked at 16 individuals with NAFLD.  These participants were randomized to receive either 4 grams per day of Omega-3 Essential Fatty Acids or a placebo.  Red blood cell counts (RBC) of DHA were taken at the beginning of the study and at the end of the study.  Additionally various parameters of NAFLD, hepatic and whole-body insulin sensitivity, existing liver fat, triglyceride levels, Fatty Acid (FA) oxidation and DNL(de novo lipogenesis), were also assessed.  Significant improvements in hepatic insulin sensitivity (not whole body insulin sensitivity) and liver metabolism were seen in participants whose red blood cell (RBC) DHA levels increased by over 2%.  A 26% reduction in existing liver fat content was also seen although this was not considered statistically significant.

No guidelines were given to the participants to avoid consuming oily fish during the trial period which most likely accounted for one of the placebo group participants showing increased RBC DHA levels over 2%.  Another drawback of the study design was that the primary outcome studied by researchers was the effect of raising RBC DHA on NAFLD markers.  No attempt to determine if EPA levels had any effect on these markers was made.  Future testing might attempt to determine the effect a DHA only oil would have on NAFLD markers.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY!

http://naturesvitaminsonline.com

http://earthwiself.com

 

Advertisements

Omega-3 Supplements May Slash Cardiac Death Risk

Omega-3 Reduces Cardiac Death RiskAccording to a new meta-analysis supplementing with Omega-3 Essential Fatty Acids may reduce the risk of coronary mortality by an average of 8%.  The reduction in the risk of death in people with elevated LDL cholesterol or triglycerides was higher at 17%.

Data from 14 randomized controlled trials (RCTs) which encompassed over 71,000 participants was reviewed.  Each of the trials lasted over 6 months and looked at cardiac deaths as the primary outcome.  Researchers compared frequencies of coronary mortality between groups supplementing with Omega-3 Essential Fatty Acids and the control groups.  In addition to seeing the statistically significant 8% reduction in cardiac death risk for participants supplementing with Omega-3’s, participants who were supplementing with more than 1 gram of total Omega-3’s (EPA and DHA) saw a reduction of cardiac death of almost 30%.

According to the Centers for Disease Control and Prevention (CDC) cardiac deaths account for almost 66% of all cardiovascular disease deaths in the United States and 42% of all cardiovascular disease deaths in the world yearly.  The results of this meta-analysis match up with the conclusions in a recent Science Advisory put out by the American Heart Association which points to EPA and DHA Omega-3 supplementation as being a “reasonable” secondary preventive measure of coronary heart disease and sudden cardiac death.

More studies are planned.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

Short-Term Fish Oil Consumption Helps Prevent Type-2 Diabetes in People with Existing Metabolic Disorders

Omega-3 and DiabetesAccording to a new meta-analysis supplementation with Omega-3 Essential Fatty Acids could increase insulin sensitivity and reduce the risk of diabetes in people who suffer from metabolic disorders.

17 studies with over 670 participants over the age of 18 were reviewed by researchers.  In individuals experiencing at least one symptom of a metabolic disorder Omega-3 supplementation heightened their insulin sensitivity, however the same benefits were not seen the participants who were healthy or already had Type-2 Diabetes.  A 47% decrease in insulin resistance was seen in the group supplementing with Omega-3 and had metabolic disorders but did not have Type-2 Diabetes.

Researchers found that serum Omega-3 polyunsaturated fatty acid levels took approximately 4 weeks to reach equilibrium.  They stressed that duration of supplementation and not dosage was crucial for the Omega-3 to be most effective.

More research is needed.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

Low Omega-3 Levels Linked to Prenatal Depression

Omega-3 and Prenatal DepressionA new study shows an Omega-3 deficiency as well as increased inflammation may be associated with prenatal depression (PND).  Also an Omega-3 deficiency may result in longer episodes of depression.

33 women (17 women with PND and 16 healthy women) in their second and third trimesters of pregnancy participated in this study.  Their inflammatory markers, tumor necrosis factor alpha (TNF-a) as well as their Omega-3 levels were measured.  The women who experienced PND had significantly higher TNF-a levels and significantly lower Omega-3 levels.

These finds confirm other observational studies that show higher levels of total Omega-3 (DHA  and EPA) seem to act as “protective factors” against major depressive disorder (MDD).  Also larger DHA levels found in breast milk and increasing the consumption of DHA rich foods, like seafood, have been shown as links to decreased risks of postpartum depression.  Omega-3 deficiencies seen during pregnancy may also increase the length of the depressive episodes which could last even into the first year after delivery.  This could lead to psychosocial dysfunction, suicide, poor mother-child relationships, and destructive behaviors like alcohol and drug abuse according to this study.

Future larger sample size studies are needed to replicate the findings in this study.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

 

 

 

Meta-Analysis Supports Potential of Omega-3s for ADHD

Omega-3 and ADHDAccording to a new meta-analysis of “gold standard” clinical studies, Omega-3 essential fatty acid supplements could improve symptoms and cognitive performance in adolescents and children with attention deficit hyperactivity disorder (ADHD).

Data taken from seven randomized controlled trials (RCTs) and involving over 500 youth was analyzed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.  The data used was taken from established scientific literature databases to insure only appropriate studies were included in this meta-analysis.

Researchers found that supplementation with Omega-3 essential fatty acids significantly improved hyperactivity and inattention symptoms. Improvements in hyperactivity were only seen when doses of EPA (eicosapentaenoic acid) were over 500 mg/day.  Additionally data from case-control studies were also taken to determine if Omega-3 levels were associated with ADHD.  Results showed that adolescents and children with ADHD had lower levels of EPA, DHA and total Omega-3.  Improvements in certain measures of cognitive performance were also associated with Omega-3 supplementation.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

 

Omega-3 and Arthritis: Study Finds Link Between Fish Consumption and Joint Disorder

Arthritis Omega-3New data finds regular consumption of fish rich in Omega-3 Essential Fatty Acids may reduce symptoms of Rheumatoid Arthritis.

Over 170 patients were assessed for Rheumatoid Arthritis scores using the DAS28-CRP scale.  Their intake of Omega-3 Essential Fatty Acids were assessed using a food frequency questionnaire

Researchers found a dose-response relationship between RA scores and Omega-3 Essential Fatty Acid intake, increasing Omega-3 Essential Fatty Acids reduced the activity of the disease.

More studies are needed.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com

Omega-3 Deficient Teenagers May Become Anxious Adults

Omega 3 AnxietyA new study using mice has found low Omega-3 in adolescent mice may lead to behavioral problems in adulthood.

Using a mouse model which mimicked a dietary deficiency of Omega-3 Essential Fatty Acids during childhood and adolescence, researchers found significant increases in anxiety and anhedonia (the inability to experience pleasure from activities usually found enjoyable).  The increases in these conditions can lead to decreases in specific cognitive functions during adulthood.  Researchers found switching the diet of the mice to one lacking Omega-3’s during adolescence led to lower Poly Unsaturated Fatty Acid (PUFA) levels in various areas of the brain during the adulthood of the mice.  These lower Omega-3 levels in these affected areas of the brain impacts a signaling mechanism known as mGlu5-endocannabinoid.  This signaling mechanism results in the changes seen in cognitive and emotional functions.

Omega-3 Essential Fatty Acid deficiency is widely believed to be a major risk factor associated with conditions like schizophrenia, bipolar disorder and depression.  Current research has shown the importance of high Omega-3 status during important development periods like perinatal and adolescent life stages.

ASK US.  WE KNOW.  NOBODY KNOWS NUTRITION LIKE WE DO.  NOBODY !

http://naturesvitaminsonline.com

http://earthwiself.com