Curcumin Touted For Metabolic Benefits in People with Fatty Liver Disease

LiverA new study suggests daily supplementation with Curcumin (Turmeric) might improve Body Mass Index (BMI), metabolic status and liver biomarkers in people with Non-Alcoholic Fatty Liver Disease (NAFLD).

87 people with grades 1-3 NAFLD (Non-Alcoholic Fatty Liver Disease) participated in this randomized controlled clinical study.  The study lasted 8 weeks.  Participants were assigned randomly to receive either a 1,000 mg daily dosage (divided into 2 doses) of Curcumin or a placebo.  Researchers found a statistically significant reduction in BMI, .99 points in the group supplementing with Curcumin compared to .15 points in the group taking the placebo.  Additionally waist circumference decreased by 1.74 for those taking the Curcumin compared to a reduction of .23 in the group supplementing with the placebo.  Also, Ultrasonographic findings were improved in 75% of the participants in the Curcumin group compared to an improvement in 4.5% of the placebo group.  Curcumin was also associated with a reduction in LDL cholesterol, total cholesterol, triglycerides, non-high density lipoprotein cholesterol and uric acid levels.

NAFLD is the most common type of chronic liver disorders and affects approximately 30% of the population and between 60 – 70% of individuals who have diabetes or who are obese.

Further studies are needed.

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Curcumin Supplementation Shows Benefits For People With Severe Depression

Curcumin and DepressionA new study has found that daily supplementation with Curcumin may be effective in reducing anxiety and depressive symptoms in people with major depressive disorders.

Over 100 people participated in this randomized, double-blind, placebo controlled study.  All the participants had major depressive disorder.  Participants were given one of four treatment conditions: A placebo, a low-dose Curcumin Extract (250 MG), a high dose Curcumin Extract (500 MG), or a combined saffron (15 MG) plus low-dose Curcumin Extract (250 MG).  The study lasted 12 weeks.  The Inventory of Depressive Symptomatology self-rated version (IDS-SR30) and the Speilberger State Trait Anxiety Inventory (STAI) were used to measure results.

Participants supplementing with any form of the Curcumin Extract saw considerable improvements when compared to the placebo group.  No differences were seen between the different doses of Curcumin Extract or the combination of the Curcumin/Saffron.

Researchers believe that larger studies are needed.  They also believe the treatment duration needs to be longer.

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