Could Probiotics Restore Microbiome Imbalance Linked to Auto-Immune Disorder?

Probiotics and ImmuneA new study finds that probiotics may aid in restoring imbalances in gut bacterial in patients with the auto-immune disorder systemic sclerosis.  Systemic sclerosis affects connective tissue in the body.  It is not a common condition, but results in the skin thickening and becoming hard.  Occasionally this condition creates problems with blood vessels and internal organs.

17 adults with systemic sclerosis from UCLA, 17 adults with systemic sclerosis from Oslo University Hospital and 17 healthy adults participated in this trial.  Stool specimens were used to determine the amount and types of bacteria present.  Participants with systemic sclerosis had significantly lower amounts of gut bacteria believed to protect against inflammation like Bacteroides.  Additionally the participants with systemic sclerosis were found to have higher amounts of bacteria, like Fusobacterium, which actually promote inflammation when compared to those without this auto-immune disorder.

Researchers believe that probiotics are helpful in restoring the bacterial balance in the gut in individuals suffering from systemic sclerosis and play a role in improving these patients quality of life.

Further testing is planned using larger patient groups.

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