Metabolic Syndrome Patients Need More Vitamin C to Break Cycle of Antioxidant Depletion

etabolic Syndrome and Vitamin CResearchers say a higher intake of Vitamin C is necessary for metabolic syndrome patients trying to stop a potentially deadly cycle of health-related problems and antioxidant disruption.  35% of the adult population in the United States is believed to suffer from metabolic syndrome.

Saturated fat, which is high in many people’s diets here in the U.S., causes chronic low-grade inflammation in the body.  This chronic inflammation is believed to lead to the development of metabolic syndrome.  Metabolic syndrome is associated with dementia, cardiovascular disease, type 2 diabetes, cognitive dysfunction and fatty liver disease. A person with at least 3 of these conditions is considered to have metabolic syndrome: high triglyceride levels, low HDL cholesterol (good cholesterol), high blood sugar, high blood pressure and abdominal obesity.

It is believed that an imbalance in gut microbiomes caused by eating high amounts of saturated fats contributes to toxins in the bloodstream which in turn causes Vitamin C depletion and subsequently impairs Vitamin E benefits.  Antioxidants like Vitamin C and Vitamin E protects against oxidative stress caused by inflammation and free radicals, unstable molecules that harm the body’s cells.  Vitamin C is known to protect Vitamin E, so when you have lipid peroxidation (the process by which free radicals try to find a way to stabilize themselves by stealing electrons from cell membranes which causes damage to cells) Vitamin E gets used up and Vitamin C regenerates the Vitamin E.  Without Vitamin C, Vitamin E is lost and your body ends up in a vicious cycle of depleting the body’s natural antioxidants protections.

Injury to the gut occurs when there is too much fat in the diet.  Bacterial cell walls might begin to leak from the gut and begin circulating in the body causing neutrophils, the most abundant type of white blood cells, to chase them down.  Neutrophils attack bacteria and that destroys Vitamin C.  This process keeps repeating without intervention.  People with metabolic syndrome can have the same amount of Vitamin C in their diet as individuals without metabolic syndrome but they will have lower plasma concentrations of Vitamin C. So increases in supplementation or dietary intake are a must.




Endurance Exercise Maximizes Impact of Vitamins C and D on Metabolic Syndrome

Endurance Exercises-Vitamins-Metabolic SyndromeCurrent research shown while Vitamin C and Vitamin D can alleviate metabolic syndrome combing exercise with these supplements maximizes the impact to alleviate metabolic syndrome.

Over 150 individual’s ages between 30 to 50 years of age participated in the Randomized Controlled Trial.  Participants were assigned to one of six groups: Vitamin C group: participants took 500 mg of Vitamin C supplements daily.  Vitamin C plus PA: participants took the same dosage of Vitamin C at either 7:30 am or 3:00 pm and completed 30 minutes of daily endurance exercise.  Vitamin D group: participants took 2000IU of Vitamin D supplements daily in the morning.  Vitamin D plus PA: participants took the same dosage of Vitamin D at either 7:  amor 3:00 pm and completed 30 minutes of daily endurance exercise.  Placebo Groups: one group received a placebo and participated in 30 minutes of daily endurance exercise and the other group did not participate in the exercise but received the daily placebo supplement.  The study period lasted for 3 months and researchers collected data during this period.

Researchers found the Vitamin D had a larger influence on metabolic syndrome than the Vitamin C when evaluating the effects these supplements had on blood pressure, LDL cholesterol, total cholesterol and fasting plasma glucose levels.  The Vitamin C however was more effective for reducing HDL and triglyceride levels as well as waist circumference.  Individuals in the Vitamin D plus PA group showed lowered systolic blood pressure which was not seen in the Vitamin C group.

The main limitations of the study were its small sample size and short study period.



Calcium & Magnesium Reduce Risk of Metabolic Syndrome

Metabolic Syndrome and Calcium-MagnesiumA new study found calcium and magnesium may reduce metabolic syndrome risk. Over 9000 adults participated in this research.  Using 24 hour recalls researchers found women who met US RDA’s on these minerals (Magnesium 310 – 320 mg/day and Calcium (1000 – 1200 mg/day) experienced the largest reduction in metabolic syndrome risks.  Men however had to increase their intakes of these minerals (Magnesium over 386 mg/day and Calcium over 1224 mg/day) to experience metabolic syndrome risk reductions.  It was not understood why these differences occurred between men and women.  Triglyceride levels and HDL cholesterol levels in addition to glucose levels were used as markers of metabolic syndrome. Metabolic syndrome is defined as a “clustering of metabolic traits”.  These traits include glucose intolerance, high blood pressure, abdominal obesity and high levels of fats in the blood (dyslipidaemia).  Increases in diseases like type 2 diabetes, cardiovascular disease and certain types of cancer are associated with metabolic syndrome. Metabolic syndrome has increased from 23.7% of adults over the age of 20 in 1988-1994 to 34.2% of adults in 1999-2006. Further research is needed. ASK US. WE KNOW. NOBODY KNOWS NUTRITION LIKE WE DO. NOBODY!

Could Low Vitamin D Put Postmenopausal Women At a Higher Risk of Metabolic Syndrome?

According to new data the onset of Metabolic Syndrome (MetS) in postmenopausal women may be closely linked to Vitamin D deficiency.  Metabolic Syndrome (MetS) was seen in 58% of postmenopausal women with either deficient or insufficient levels of Vitamin D when compared with a 40% occurrence in women with adequate Vitamin D levels.

Over 450 women participated in this study.  Participants ages were between 45 and 75 years and all participants had stopped menstruating for at the minimum of 1 year prior to the beginning of the study.  Additionally none of the participants had experienced any type of Cardiovascular Disease at the baseline.  35% of the participants were Vitamin D deficient and 33% of the participants had insufficient levels of Vitamin D.  A Vitamin D deficiency is usually defined as blood levels below 50 nanomoles/liter (nmol/L) and an insufficient Vitamin D level is defined as a blood level between 50 – 75 nmol/L.

Blood levels of the participants Vitamin D levels were measured and compared to the analyzed Metabolic Syndrome parameters of the participants.  Researchers found the lower the blood level of Vitamin D the greater the occurrence of Metabolic Syndrome.  Additionally researchers found an inverse relationship between blood triglycerides and HDL levels, 2 individual components of Metabolic Syndrome and Vitamin D levels.

Metabolic Syndrome involves a group of conditions that increase a person’s risk for stroke, heart disease and diabetes.    For the purposes of the study, participants meeting 3 of more of the criteria listed below were considered to have Metabolic Syndrome:

Waist circumference above 88 cm

High Blood Pressure (above 130/85 mmHG)

High Blood Sugar (fasting glucose levels over 100 mg/dl)

Abnormal triglycerides (above 150 mg/dl)

HDL below 50 mg/dl

Further studies are needed.


Curcumin May Improve Cholesterol Levels for People with MetS

Curcumin and High CholesterolA new study showed daily supplementation of the yellow pigment from turmeric, curcumin, may support lower LDL cholesterol and triglyceride levels in individuals with metabolic syndrome.

65 people with metabolic syndrome participated in this placebo controlled double blind study.  Individuals were assigned randomly to receive either 630 mg of curcumin 3 times per day or a placebo.  The study lasted 12 weeks.  LDL levels decreased significantly from an average of 121 to 107 while triglycerides dropped an average of 65 mg/dl.  HDL levels increased from 41 to 43 mg/dl.  Men saw more benefits for cholesterol lowering while women saw better improvements in good cholesterol (HDL).

Metabolic syndrome is characterized by hypertension, obesity and disturbed glucose and insulin metabolism.  Metabolic syndrome has been linked to increased risks of cardiovascular disease as well as type 2 diabetes.


CoQ10 May Help Blood Sugar Management in People with Metabolic Syndrome

Metabolic SyndromAccording to a new study daily CoEnzyme Q10 supplementation may produce a beneficial effect on blood sugar management and insulin in people with metabolic syndrome.

60 individuals with metabolic syndrome were randomly assigned to receive either a placebo or 100 mg of CoQ10 daily.  The study lasted 8 weeks.  Participants ranged in age from 40 to 85.  Individuals in the CoQ10 group saw significant improvements in insulin resistance as measured using the homeostatic model assessment HOMA-IR, serum insulin levels and beta-cell function measured using the homeostatic model assessment beta cell function HOMA-B.  Reductions in markers for oxidative stress and improvements in glutathione levels were also observed.  No changes however, were observed for fasting blood sugar levels, markers of inflammation or cholesterol levels.

CoQ10 is a cell oxygenator and aids in the transport of energy from cell to cell.  This keeps the body in an aerobic state of metabolism and provides a strong antioxidant benefit.

Metabolic syndrome (MetS) is a condition characterized by obesity, disturbed glucose and insulin metabolism and hypertension.  Metabolic Syndrome is also believed to increase the risks of developing cardiovascular disease and type 2 Diabetes.

When searching out a CoEnzyme Q10 product make sure the product is processed through a natural fermentation process and is not synthetic.  Also make sure the product is the trans form of the CoQ10 which is the most active form and that the product contains no cis-isomers.



Small Fish Oil Doses Enough to Lower Blood Pressure — Nature’s Vitamins

A new study finds that in individuals with a history of hypertension, even the smallest amount of fish oil may reduce blood pressure. Over 300 healthy women and men between the ages of 20 and 70 participated in this randomized controlled trial. Participants consumed either a placebo made from palm and soybean oil or a…

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