Chondroitin Sulfate as Good as Widely Used Anti-Inflammatory Drug for Knee Osteoarthritis

Chondroitin and Knee OsteoarthritisNew research shows a high quality Chondroitin Sulfate supplements may be as effective as a very commonly prescribed non-steroidal anti-inflammatory medication for treating knee osteoarthritis.

Over 600 individuals with symptomatic knee osteoarthritis were randomly assigned to receive one of three different daily treatments.  Participants were then monitored for six months.  One group was given an 800 mg tablet of Chondroitin Sulfate and a 200 g tablet of a fake version of the anti-inflammatory drug Celebrex.  Group two was given a fake tablet of Chondroitin Sulfate and one Celebrex.  The final group was given a fake tablet of Chondroitin Sulfate and a fake tablet of Celebrex.  Participants were then assessed using a validated scoring system to gauge the overall acceptability of the assigned protocol, joint function and pain levels at 30 days, 91 days and 182 days.

Pain reductions were significantly greater after six months and joint function showed improvements in three months in groups receiving either the Chondroitin Sulfate or the Celebrex.  Although there were no differences in the overall effectiveness of either active treatment (both the Celebrex and the Chondroitin Sulfate treatments were highly rated by participants) joint function improved more quickly in participants taking the Celebrex.

Researchers concluded a higher quality Chondroitin Sulfate should be the first treatment considered for this condition due to the known risks for continued usage of Celebrex and other non-steroidal anti-inflammatory drugs (NSAIDs).