Recent RCT Discovers Vitamin D Deficiency May Double the Risk of Preeclampsia in Pregnant Women

Vitamin D and Pre-EclampsiaA new study finds that gestational hypertension/preeclampsia could be reduced with Vitamin D supplementation therapy.

Over 140 women with a history of preeclampsia participated in this study.  Women with hypertension before their pregnancy, a history of pulmonary, renal or cardiac disease and Vitamin D levels above 25 ng/ml (optimal Vitamin D levels are considered to be between 40 – 60 ng/ml) were excluded from the trial.    Vitamin D levels were taken at baseline.  70 of the participants (the intervention group) received a 50,000 IU Vitamin D supplement every two weeks.  The remaining participants (the control group) received a placebo.  The study lasted until the 36th week of pregnancy.  The control group experienced a 1.94 times increase in the risk of developing preeclampsia when compared to the intervention group.

Preeclampsia is a form of high blood pressure (hypertension) related to pregnancy and is characterized by excess protein in the urine and high blood pressure.  This condition is fairly easy to treat but can be very harmful to both the child and the mother and accounts for approximately 25% of all maternal deaths.  Preeclampsia also increases the risk the baby will be born prematurely or small for their gestational age with increases the risk of infant mortality.

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Study Underscores Positive Effect of Vitamin D on Female Fertility

Vitamin D and Female FertilityNew research linking Vitamin D levels to regulation of ovarian hormones shows Vitamin D status may play an essential role in female reproduction and fertility.

49 women, ages 19 through 25, participated in this study.  The criteria for women to participate in this research were as follows:

Participants must have regular menstrual cycles

Participants could not be pregnant

Participants had not breastfed within the past two months

Participants had not supplemented with Vitamin D

Participants had not travelled to the northern hemisphere

Participants had not used a tanning booth or sunbed

Participants were given a Vitamin D supplement or a placebo during the week after their menstrual period began.  Changes in AMH levels (anti-Mullerian hormone levels) were analyzed. The anti-Mullerian hormone is an ovarian regulator however; its function is largely unknown.  Results of the study showed a single dose of oral Vitamin D generated a sharp change in the serum levels of 25(OH)D (the most accurate measure of Vitamin D in the body).  A progressive rise in the participants AMH levels was also seen.  These findings support the theory the Vitamin D has a positive effect on a women’s fertility and may involve the regulation of AMH levels.

Researchers strongly suggest further clinical studies are needed.

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Vitamin D and Calcium May Reduce Onset of Early Menopause

Calcium Vitamin D Early MenopauseA new study shows a reduction in the risk of early menopause when high doses of dietary Vitamin D and Calcium are taken.  Early menopause is associated with higher risks for Osteoporosis, Early Cognitive Decline, Cardiovascular Disease and other health issues.

Over 116,000 female US registered nurses participated in this study.  Individuals between the ages of 25 and 42 in 1989 participated in this study and responded to a questionnaire.  Intakes of Vitamin D and Calcium from both supplements and food were measured every four years and medical conditions and behaviors were measured every two years. Over 2000 women reported having natural menopause before 45 years of age.  Incidents of possible confounding factors were accounted for when evaluating the relationship between the intake of Calcium and Vitamin D and incidents of early menopause.

A 17% lower risk of early menopause was seen in the women who had the highest intake of Vitamin D when compared with the women who had the lowest intake of Vitamin D.  A “borderline significantly lower risk” of early menopause was seen in the women with the highest intake of Calcium when compared to the women with the lowest intake of Calcium.

Further studies are now being undertaken.

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Vitamin B’s Women’s Benefits: Supplementation Boosts Convention Yeast Infection Treatment RCT Finds

B VitaminsAccording to a new study supplementing with Vitamin B along with doing the conventional treatment can help treat complicated cases of vulvovaginal candidiasis (VVC).  VVC is a fungal infection caused by the Candida species, the second major cause of vaginitis in women, with the first major cause being bacterial vaginitis.  75% of women are infected with VVC at least once in their life prior to menopause.  5% of these women experience VVC on a recurrent basis.

Over 150 women with VVC participated in this study and were randomly assigned into groups as follows: Group A (received a suppository and oral antifungal) Group B (received a suppository and a vaginal cream) and Group C (received a suppository, vaginal cream and a Vitamin B Complex supplement).  Patients in Group C (92.73%) saw a significantly higher rate of treatment success, percentage of patients with recovery, marked effective and improvement, in comparison to Groups A (73.47%) and B (79.63%).  The recovery rate alone was also higher in Group C (72.73%) compared with Group A (61.22%) and Group B (62.96%).

Researchers concluded the Supplementing with Vitamin B Complex might be an effective additional therapy for treating complicated VVC.

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Green Tea Extract Supplements May Improve Lipid Levels For Women

cholesterolA new study found supplementing with Green Tea Extract may lower both total cholesterol and LDL cholesterol levels in post-menopausal women. The cholesterol lowering effects of the Green Tea Extract was even stronger in women whose total cholesterol at baseline (the onset of the study) where high.

Over 1000 women participated in this randomized controlled study.  Participants were randomly assigned to take the Green Tea extract or a placebo.  The study lasted 1 year.  936 women ended up completing the study.  A 2.1% reduction in total cholesterol and a 4.1% reduction in LDL cholesterol were seen in the group taking the Green Tea Extract in comparison to increases of .7% in total cholesterol levels and .9% in LDL cholesterol levels in women taking the placebo.

One of the phytonutrients in the Green tea, EGCG (epigallocatechin gallate), is believed to be the most bioactive catechin in Green Tea and most likely to be responsible for Green Extract’s hypolipidemic effect.

Make sure your Green Tea Extract is standardized to at least 50% Catechins.  Standardization assures you are getting the same dosage in every capsule or tablet of the phytonutrient in the herb that gives that herb it’s beneficial properties.

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Red Wine Compound Can Reset Infertility Hormones

resveratrolAccording to a new study Resveratrol, a compound found in Red Wine, may help tackle a hormone disparity in women with a common condition that could cause infertility, polycystic ovary syndrome (PCOS).  PCOS causes an overproduction of the hormone testosterone and has been determined to affect between 6 to 8% of all women who are of reproductive age.  Other hormones like DHEAS (dehydroepiandrosterone sulphate) are also produced in excessive amounts.

Women with PCOS experience absent or irregular menstrual periods, infertility or increased facial and body hair.  Women with PCOS also have a higher risk of developing diabetes.

30 women with PCOS participated in this randomized, double blind, placebo-controlled study.  The study lasted 3 months.  Hormone levels of testosterone and other hormones were determined by participants who gave blood samples at the beginning and at the end of the study period.  Tests to determine glucose tolerance were also given at the beginning and the end of the study to assess the risk factors for diabetes.

Resveratrol has been identified in prior studies to aid in regulating excess hormone production in the ovaries and in its ability to hamper cell multiplication and growth without any cytotoxic effects.  Additionally studies have shown Resveratrol may lower the risk of developing diabetes by aiding the body’s ability to utilize insulin.

Researchers found testosterone levels dropped by 23.1% in the participants supplementing with Resveratrol in comparison with those supplementing with the placebo who saw a 2.9% increase in testosterone levels.  DHEAS levels declined by 22.2% in the Resveratrol group and rose 10.5% in the group supplementing with the placebo.

Further studies are needed.

Resveratrol, a compound found in Red Wine, has been shown to support a healthy heart in addition to providing the anti-aging benefits associated with a reduced calorie diet which in turn aids in supporting the overall health of living cells.

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